"Oprah’s great. I just think the only misconception is that she’s a Black woman." Those were 50 Cent’s words backstage at "106 & Park" last Thursday, according to BET.com. 50 added that Oprah has been catering to a demographic of middle-aged white women for so long that he now believes she’s a middle-aged white woman herself. You would recall that the G-Unit General spoke out against Oprah back in April, 2006, after word began to spread about the talk show host’s anti-hip-hop sentiments.
Oprah will have a rapist on her show and have a discussion about why they do it, but won’t have a rags-to-riches story on her show," 50 quipped. He also had some harsh words about Kanye West’s appearance on the show. "She’ll have Kanye West on her show. I think middle America would rather have they kids be gay than have them aggressive."
The verbal war against Oprah began after rapper/actor Ludacris complained that Oprah had been unfair to her during an appearance with his "Crash" co-stars on the talk-show. 50 Cent then joined the outcry saying that Oprah "caters to older white women." Oprah responded to 50′s outcry during a surprise appearance on Power 105.1 FM, stating that she even has 50 Cent’s "In da Club" on her iPod. "I listen to some hip-hop," she told DJ Ed Lover. "You know, I’ve been accused of not liking hip-hop and that’s just not true." She also shot down the anti-hip-hop rumor, citing Jay-Z and Kanye West as some of her favorite rappers.